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For patients with liver lesions larger than 1 cm who are at risk for HCC, a diagnosis should be established.

The tests required to diagnose HCC may include imaging, biopsy, or both.

Untreated patients with advanced disease usually survive less than 6 months.[27] The survival rate of untreated patients in 25 randomized clinical trials ranged from 10% to 72% at 1 year and 8% to 50% at 2 years.[28] Unlike most patients with solid tumors, the prognosis of patients with HCC is affected by the tumor stage at presentation and by the underlying liver function.

The following prognostic factors guide the selection of treatment: Prognostic modeling in hepatocellular carcinoma (HCC) is complex because cirrhosis is involved in as many as 80% of the cases.

The liver is in the upper abdomen near the stomach, intestines, gallbladder, and pancreas. Two lobes are on the front and two small lobes (not shown) are on the back of the liver.

For lesions that are smaller than 1 cm and are detected during screening in patients at high risk for HCC, further diagnostic evaluation is not required because most of these lesions will be cirrhotic lesions rather than HCC.[16][Level of evidence: 3iii] Close follow-up at 3-month intervals is a common surveillance strategy, using the same technique that first documented the presence of the lesions.From whimsical Park Guell to the epic grandeur of La Sagrada Familia - art simply lives here.If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware.Finding a mass in the liver of a patient with an elevated AFP does not automatically indicate HCC.However, if the AFP level is high, it can be used to monitor for recurrence.Clinical use of TNM staging is limited because liver function is not considered.

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