The movie tells the story of a woman (played by Renée) who is forced to put her life on hold in order to care for her mother who is dying of cancer.
One True Thing took in a modest US million in the US, Variety magazine's Todd Mc Carthy stated about Zellweger: "Projecting gravity and impatience that she hasn't shown before, Zellweger is outstanding as the smart young woman who resents the interruption to her life’s momentum but ends up growing in ways she never would have expected." For her work in both A Price Above Rubies and One True Thing, she tied with Central Station's Fernanda Montenegro as runners-up for the Best Actress prize at the 64th New York Film Critics Circle Awards, It revolves around a Rhode Island state trooper with split-personality disorder named Charlie, played by Carrey, who is assigned to escort Irene from Rhode Island to Massena, New York, to face what she believes is a false hit-and-run accusation set up by her mob-connected ex-boyfriend.
She won the Academy Award, the BAFTA Award, the Golden Globe Award, and the Screen Actors Guild Award for Best Supporting Actress for the epic war drama Cold Mountain (2003).
She subsequently starred in the romantic comedy Bridget Jones's Diary (2001), obtaining nominations for the Academy Award and BAFTA Award for Best Leading Actress.
Her role in musical Chicago (2002) earned her another Oscar nomination for Best Actress, and her second Golden Globe Award.
; born April 25, 1969) is an American actress and producer.
She has received critical acclaim and many accolades, including an Academy Award, a BAFTA Award, three Golden Globe Awards, and three Screen Actors Guild Awards.
 After citing “fraud” as the reason for annulling your marriage to Kenny Chesney in 2005, many media outlets alleged that he must be gay. I’m an old-fashioned gal who doesn’t feel it’s appropriate to hang out your laundry on the lawn.
Of course, there’s the bigger-picture problem of why anyone had to make up a story at all. Well, I’d said all I needed to say on that subject.
It received a release in selected theaters, garnering mostly favorable comments from critics.
Marc Savlov of Austin Chronicle applauded the main cast saying they were "all excellent in their roles" and noted that "Zellweger's character – all squeals and caged sexuality – seems a bit too close to Juliette Lewis' Mallory Knox (of Natural Born Killers) to be as fresh as it should be".
However, Janet Maslin of The New York Times, praised her and co-star Mc Conaughey, remarking that both "do show signs of what would soon make them famous. Zellweger, sweet and sprightly and a natural-born ditz, may be the only actress who could point a gun bravely at a killer, then simply shriek and drop it and scamper away".